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ACVR1C

ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Leydig cells, Excitatory neurons, Proximal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (ASC diff, HDLM-2)

Interaction

Binds the type 2 receptor protein ACVR2A.

Molecular function

Kinase, Receptor, Serine/threonine-protein kinase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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