Enzymes
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts (via RING-type zinc finger 1) with UBE2L3 (PubMed:16118314, PubMed:19340006, PubMed:24076655). Interacts (via RING-type zinc finger 2) with UBE2N (PubMed:19340006). Interacts with neddylated CUL5 (PubMed:24076655). Interacts (via RING-type 2) with GFI1B (PubMed:17646546). Interacts with GFI1; prevents its ubiquitination and proteasomal degradation (PubMed:17646546). Interacts with DCUN1D1 (via UBA-like domain); promotes DCUN1D1 ubiquitination (PubMed:30587576).
Transferase
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For Research Use Only. Not For Clinical Use.