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bapi
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- Recombinant Anti-human bapi Antibody (MOB-100)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
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- Recombinant Human Anti-human bapi Antibody Fab Fragment (MHH-100-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: FC, RIA, Biosensors, FuncS
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- Recombinant Human Anti-human bapi Antibody scFv Fragment (MHH-100-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: FC, Neut, Biosensors, FuncS
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- Recombinant Anti-human bapi Antibody Fab Fragment (MOB-100-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FuncS
Compare
- Recombinant Anti-human bapi Antibody scFv Fragment (MOB-100-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IHC, FuncS
Compare
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For Research Use Only. Not For Clinical Use.
Background
Bapineuzumab (nicknamed "bapi") is a humanized monoclonal antibody that acts on the nervous system and may have potential therapeutic value for the treatment of Alzheimer's disease and possibly glaucoma. However, in 2012 it failed to produce significant cognitive improvements in patients in two major trials, despite lowering key biomarkers of AD, amyloid brain plaque and phosphorylated Tau protein in CSF.