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CARNMT1
The protein encoded by this gene is a methyltransferase that converts carnosine to anserine, a dipeptide found abundantly in skeletal muscle. The encoded protein can methylate other dipeptides as well. Three transcript variants encoding two different isoforms have been found for this gene.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Each monomer accommodates one molecule of carnosine in its active pocket (residues 313-398), precisely anchoring the histidine imidazole ring such that only N1 is exposed and deprotonated for methylation.
Molecular function
Methyltransferase, Transferase
More Types Infomation
- Mouse Anti-CARNMT1 Recombinant Antibody (clone 7B3) (MOB-2276MZ)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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For Research Use Only. Not For Clinical Use.