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CD180

CD180 (CD180 Molecule) is a Protein Coding gene. Among its related pathways are Innate Immune System and Activated TLR4 signalling. An important paralog of this gene is TLR4.
Protein class

CD markers

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Hofbauer cells, B-cells, Plasma cells, Kupffer cells, Macrophages, monocytes)

Immune cell specificity

Immune cell enhanced (naive B-cell, memory B-cell)

Cell line specificity

Group enriched (Daudi, Karpas-707, U-266/70, U-266/84, U-698)

Interaction

M-shaped tetramer of two CD180-LY86 heterodimers.

Molecular function

Receptor

More Types Infomation
    • Target: CD180
    • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
    • Target: CD180
    • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
    • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)

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