Disease related genes, Enzymes, Metabolic proteins, Potential drug targets
Intracellular
Cell type enhanced (Early spermatids, Late spermatids, Spermatocytes)
Immune cell enhanced (T-reg)
Low cell line specificity
Interacts with cyclin-dependent kinases such as CDK1, CDK2 and CDK3. Does not interact with CDK4. Interacts (via C-terminus) with phosphorylated CDK2 (via C-terminal helix). Interacts with MS4A3 (via C-terminus); the interaction enhances CDKN3 enzymatic activity.
Hydrolase, Protein phosphatase
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For Research Use Only. Not For Clinical Use.