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CLDN4

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The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Derivation:
Humanized
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Derivation:
Chimeric (mouse/human)
Type:
Chimeric antibody (mouse/human)
Derivation:
Humanized
Type:
Humanized antibody
Derivation:
Chimeric (mouse/human)
Type:
Chimeric antibody (mouse/human)
Species Reactivity:
Mouse
Derivation:
Chimeric (mouse/human)
Type:
Chimeric antibody (mouse/human)
Derivation:
Humanized
Type:
Humanized antibody
Derivation:
Chimeric (mouse/human)
Type:
Chimeric antibody (mouse/human)
Species Reactivity:
Mouse
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, IP, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IF, WB, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, IHC, FuncS
Derivation:
Humanized
Species Reactivity:
Human
Type:
Antibody
Derivation:
Chimeric (mouse/human)
Type:
Chimeric antibody (mouse/human)
Derivation:
Humanized
Type:
Humanized antibody
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