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CLEC4D

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.
Protein class

CD markers

Predicted location

Intracellular

Single cell type specificity

Group enriched (monocytes, Macrophages, Kupffer cells)

Immune cell specificity

Group enriched (neutrophil, classical monocyte)

Cell line specificity

Group enriched (NB-4, NTERA-2, SuSa, U-937)

Interaction

Heterodimer with CLEC4E; disulfide-linked (By similarity). CLEC4E acts as a bridge for interaction between CLEC4D and FCER1G to form a functional complex (By similarity). Heterodimer with CLEC6A; this heterodimer forms a pattern recognition receptor (PRR) against fungal infection (PubMed:23911656).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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