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Cmklr1

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For Research Use Only. Not For Clinical Use.


Predicted to enable adipokinetic hormone binding activity; adipokinetic hormone receptor activity; and transmembrane signaling receptor activity. Involved in negative regulation of interleukin-12 production; positive regulation of cold-induced thermogenesis; and positive regulation of fat cell differentiation. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; embryo mesenchyme; jaw; lung; and uterus. Orthologous to human CMKLR1 (chemerin chemokine-like receptor 1).
Cmklr1
Protein class

G-protein coupled receptors, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Kupffer cells, Microglial cells, Hofbauer cells, NK-cells, Macrophages, dendritic cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC, intermediate monocyte)

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, hTERT-RPE1, LHCN-M2)

Molecular function

G-protein coupled receptor, Receptor, Transducer

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