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COL4A2

COL4A2 (Collagen Type IV Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL4A2 include Porencephaly 2 and Hemorrhage, Intracerebral. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is COL4A6.
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Extravillous trophoblasts, Sertoli cells, Smooth muscle cells, Adipocytes, Endometrial stromal cells, Endothelial cells, Granulosa cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (EFO-21, WM-115)

Interaction

There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. Interacts with EFEMP2 (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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