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CPLX1

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. [provided by RefSeq, Jul 2008]
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Inhibitory neurons, Adipocytes, Excitatory neurons, Bipolar cells, Endothelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SCLC-21H)

Interaction

Binds to the SNARE core complex containing SNAP25, VAMP2 and STX1A.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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