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CTAG2
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (GAMG, K-562, OE19, RPMI-8226, SK-BR-3, U-266/84)
More Types Infomation
- B*07:02/Human CTAG2 (APRGVRMAV) MHC Tetramer (MHC-CN0560)
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- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: APRGVRMAV
- Conjugate: Unconjugated
- FITC-B*07:02/Human CTAG2 (APRGVRMAV) MHC Tetramer (MHC-CN0559)
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- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: APRGVRMAV
- Conjugate: FITC
- APC-B*07:02/Human CTAG2 (APRGVRMAV) MHC Tetramer (MHC-CN0558)
-
- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: APRGVRMAV
- Conjugate: APC
- PE-B*07:02/Human CTAG2 (APRGVRMAV) MHC Tetramer (MHC-CN0557)
-
- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: APRGVRMAV
- Conjugate: PE
- A*02:01/Human CTAG2 (MLMAQEALAFL) MHC Tetramer (MHC-CN0556)
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- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: MLMAQEALAFL
- Conjugate: Unconjugated
- A*02:01/Human CAMEL (LMAQEALAFL) MHC Pentamer (MHC-YF352)
-
- Class: Class I
- Antigen: CAMEL
- Antigen Species: Human
- Peptide: LMAQEALAFL
- Conjugate: Unlabeled, Biotin, R-PE, APC
- FITC-A*02:01/Human CTAG2 (MLMAQEALAFL) MHC Tetramer (MHC-CN0555)
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- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: MLMAQEALAFL
- Conjugate: FITC
- APC-A*02:01/Human CTAG2 (MLMAQEALAFL) MHC Tetramer (MHC-CN0554)
-
- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: MLMAQEALAFL
- Conjugate: APC
- PE-A*02:01/Human CTAG2 (MLMAQEALAFL) MHC Tetramer (MHC-CN0553)
-
- Class: Class I
- Antigen: CTAG2
- Antigen Species: Human
- Peptide: MLMAQEALAFL
- Conjugate: PE
- B*07:02/Human LAGE-1 (APRGVRMAV) MHC Pentamer (MHC-YF508)
-
- Class: Class I
- Antigen: LAGE-1
- Antigen Species: Human
- Peptide: APRGVRMAV
- Conjugate: Unlabeled, Biotin, R-PE, APC
- A*02:01/HSV LANA-1 (QMARLAWEA) MHC Pentamer (MHC-YF509)
-
- Class: Class I
- Antigen: LANA-1
- Antigen Species: HSV
- Peptide: QMARLAWEA
- Conjugate: Unlabeled, Biotin, R-PE, APC
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, ELISA
- Recombinant Mouse Anti-Human CTAG2 Antibody (MOB-2016MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Recombinant Human Anti-CAMEL Soluble TCR (2/12) (C-Cys) (VS-0622-YF2765)
-
- Species Reactivity: Human
- Epitope: aa 46-65
- MHC: HLA-DR
-
- Species Reactivity: Human
- Epitope: aa 19-27 (AAQERRVPR)
- MHC: HLA-DR
-
- Species Reactivity: Human
- Epitope: aa 19-27 (AAQERRVPR)
- MHC: HLA-DR
-
- Species Reactivity: Human
- Epitope: aa 1-20
- MHC: HLA-DR
-
- Species Reactivity: Human
- Epitope: aa 46-65
- MHC: HLA-DR
- Recombinant Human Anti-CAMEL Soluble TCR (2/12) (KIH) (VS-0622-YF5473)
-
- Species Reactivity: Human
- Epitope: aa 46-65
- MHC: HLA-DR
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For Research Use Only. Not For Clinical Use.