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DLL4

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
DLL4
Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Adipocytes, Endothelial cells, Intestinal goblet cells, Hepatic stellate cells, Distal enterocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (BJ hTERT+, HUVEC TERT2, SCLC-21H)

Interaction

Interacts with NOTCH4. Interacts (via N-terminal DSL and MNNL domains) with NOTCH1 (via EGF-like domains).

Molecular function

Developmental protein

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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