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DNAJC1

DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum. GO annotations related to this gene include chromatin binding and ATPase activator activity. An important paralog of this gene is DNAJC2.
Protein class

Transcription factors

Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Interacts (via J domain) with HSPA5. Interacts (via cytosolic domain) with ribosomes (By similarity). Interacts (via SANT 2 domain) with SERPINA3; the interaction delays the formation of the covalent inhibitory complex SERPINA3-chymotrypsin, but does not alter the catalytic activity of SERPINA3. Interacts (via SANT 2 domain) with ITIH4 (via C-terminus); the interaction protects ITIH4 against in vitro cleavage by kallikrein.

Molecular function

Chaperone, DNA-binding

More Types Infomation

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