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DPP7
The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.
Protein class
Enzymes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (RPMI-8226, THP-1)
Interaction
Homodimer.
Molecular function
Aminopeptidase, Hydrolase, Protease, Serine protease
More Types Infomation
- Rat Anti-DPP7 Recombinant Antibody (clone CBL773) (NEUT-711CQ)
-
- Species Reactivity: Human
- Type: Rat IgG2a
- Application: Neut
- Rat Anti-DPP7 Recombinant Antibody (clone CBL908) (NEUT-710CQ)
-
- Species Reactivity: Human
- Type: Rat IgG2a
- Application: ELISA, Neut, WB
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.