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EDAR

The anti-EDAR monoclonal antibodies can be used in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis.
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Squamous epithelial cells, Basal squamous epithelial cells, Macrophages)

Immune cell specificity

Group enriched (naive CD4 T-cell, naive CD8 T-cell)

Cell line specificity

Cell line enhanced (CAPAN-2, HaCaT, OE19)

Interaction

Binds to EDARADD. Associates with TRAF1, TRAF2, TRAF3 and NIK.

Molecular function

Developmental protein, Receptor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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