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EMD
Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with lamins A and C, BANF1, GMCL, BCLAF1 and YTHDC1/YT521. Interacts with TMEM43; the interaction retains emerin in the nuclear inner membrane. Interacts with SUN1 and SUN2 (By similarity). Interacts with ACTB, SPTAN1, F-actin, CTNNB1 and beta-tubulin. Interacts with TMEM201.
Molecular function
Actin-binding
More Types Infomation
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- Species Reactivity: Human
- Application: ICC/IF, IHC-P, WB
- Mouse Anti-EMD Recombinant Antibody (clone 39H4) (MOB-3338z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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- Derivation: Phage display library
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC-P
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IHC-F, IHC-P, ICC, IF
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, FC, ICC
-
- Type: Mouse IgG1
- Application: IHC, ICC, FC
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, ICC, FC
- Sheep Anti-Emd Antibody (VS-0722-YJ54) (VS1-YJ54)
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- Species Reactivity: Mouse, Rat, Hamster
- Type: Sheep IgG
- Application: IB, IF
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- Species Reactivity: Rabbit, Human.Does not react with Mouse
- Type: Mouse IgG1
- Application: IB, IF, WB
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For Research Use Only. Not For Clinical Use.