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FGFR4

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The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, FC, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, Nert, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
IP, IF, Biosensors, FuncS
Species Reactivity:
Human, Mouse
Application:
ELISA, FC
Derivation:
Phage display
Species Reactivity:
Human, Mouse
Type:
Human Antibody
Application:
ELISA, FC
Species Reactivity:
Human
Application:
ELISA
Species Reactivity:
Human, Mouse
Application:
ELISA, WB
Species Reactivity:
Human
Application:
ELISA, WB, FC
Derivation:
Phage display library
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
Phage display library
Species Reactivity:
Human
Type:
Human antibody
Application:
ELISA
Derivation:
Phage display library screening
Species Reactivity:
Mouse, Rat, Human
Type:
IgG
Application:
WB
Derivation:
Phage display
Species Reactivity:
Human, Mouse, Rat, Cynomolgus monkey
Type:
Human IgG
Application:
Inhib
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib
Derivation:
Phage display
Species Reactivity:
Human, Mouse
Type:
Human IgG
Application:
Inhib, WB, ELISA
Derivation:
Phage display
Species Reactivity:
Human, Mouse
Type:
Human IgG
Application:
Inhib, WB, ELISA
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib, WB, ELISA
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib, WB, ELISA
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib, WB, ELISA
Derivation:
Phage display
Species Reactivity:
Human
Type:
Human IgG
Application:
Inhib, WB, ELISA
Species Reactivity:
Human
Type:
Human IgG
Application:
FC, ELISA, WB, IP, IHC
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