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FREM2
Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. May be required for epidermal adhesion.
Protein class
Disease related genes, Human disease related genes
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Astrocytes, Alveolar cells type 2, Proximal tubular cells, Endometrial ciliated cells, Cholangiocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, HAP1, MCF7, RT4, SK-BR-3, SuSa, WM-115)
Interaction
Interacts with FREM1.
Molecular function
Developmental protein
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IF, IP
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For Research Use Only. Not For Clinical Use.