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GATA2
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (granulocytes, Syncytiotrophoblasts, Extravillous trophoblasts, Glandular and luminal cells)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enhanced (BEWO, HEL, HMC-1, SH-SY5Y)
Interaction
Interacts with BRD3 (By similarity). Interacts with AR and CCAR1.
Molecular function
Activator, DNA-binding
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP
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For Research Use Only. Not For Clinical Use.