Secreted
Cell type enhanced (Cone photoreceptor cells, Bipolar cells, Horizontal cells, Rod photoreceptor cells)
Low immune cell specificity
Cell line enhanced (HMC-1)
Homodimer; disulfide-linked (PubMed:26919518 and PubMed:31215115). Interacts directly with ACVR2B (By similarity). Interacts directly with ACVR2A (By similarity). Interacts with ACVR1B, TGFBR1 and ACVR1C in an ACVR2B-dependent manner (By similarity). Interacts with FST isoform 2/FS-288 (PubMed:28257634).
Cytokine, Growth factor
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For Research Use Only. Not For Clinical Use.