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GDF2

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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.

Species Reactivity:
Human
Type:
IgG2
Application:
Neut, WB
Species Reactivity:
Human
Type:
IgG2b
Application:
WB, ELISA, Neut
Species Reactivity:
Human
Type:
IgG2
Application:
ELISA, WB, Neut
Species Reactivity:
Human, Mouse, Primate
Type:
IgG2b
Application:
WB, ELISA(Cap), Neut
Species Reactivity:
Mouse
Type:
Rat scFv
Application:
Inhib, ELISA
Species Reactivity:
Mouse
Type:
Rat Fab
Application:
Inhib, ELISA
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Species Reactivity:
Mouse
Type:
Rat IgG1
Application:
Inhib, ELISA
Species Reactivity:
Human
Type:
Llama VHH
Application:
ELISA, Neut, ICC, FC
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
FC, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, FC, FuncS
Species Reactivity:
Human
Type:
Antibody
Derivation:
Humanized
Species Reactivity:
Human
Type:
Human IgG1, κ
Application:
ELISA, WB
Derivation:
Humanized
Species Reactivity:
Human
Type:
Human scFv
Application:
ELISA, WB
Derivation:
Humanized
Species Reactivity:
Human
Type:
Human Fab
Application:
ELISA, WB
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