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GLYR1

GLYR1 (Glyoxylate Reductase 1 Homolog) is a Protein Coding gene. GO annotations related to this gene include methylated histone binding and phosphogluconate dehydrogenase (decarboxylating) activity. An important paralog of this gene is HIBADH.
Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homotetramere (PubMed:31408337, 30970244). Interacts with MAPK14 (PubMed:16352664). Interacts with KDM1B at nucleosomes; this interaction stimulates H3K4me1 and H3K4me2 demethylation (PubMed:23260659). Binds to mononucleosomes (PubMed:29759984). Interacts with GATA4; the interaction is required for a synergistic activation of GATA4 target genes transcription (PubMed:35182466).

Molecular function

DNA-binding, Oxidoreductase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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