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IFNL2

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
Predicted location

Secreted

Single cell type specificity

Cell type enriched (Breast myoepithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (HDLM-2)

Molecular function

Cytokine

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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