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IL6

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This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.

Scaffold Name:
Z-domain of protein A
Target:
IL-6
Species Reactivity:
Human
Derivation:
Phage display
Species Reactivity:
Chicken
Application:
WB, ELISA
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Chimeric (mouse/human)
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Humanized Antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Species Reactivity:
Cross-react with cynomolgus monkey and African green monkey IL-6
Type:
Humanized Antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Chimeric (mouse/human)
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Humanized Antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Species Reactivity:
Cross-react with cynomolgus monkey and African green monkey IL-6
Type:
Humanized Antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
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