Products
Loading...

ITM2B

More+
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia

Species Reactivity:
Human, Mouse, Rat
Type:
Chicken antibody
Application:
WB
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, IHC, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IP, RIA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
IF, Neut, FuncS
Species Reactivity:
Human, Mouse, Rat
Type:
Chicken antibody
Application:
WB
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-381-2994    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved