Transporters
Intracellular
Cell type enhanced (Cardiomyocytes, Bipolar cells, Horizontal cells, Inhibitory neurons, Cone photoreceptor cells, Excitatory neurons)
Immune cell enhanced (naive B-cell)
Cell line enhanced (HEL, HMC-1)
Component of heteromultimeric potassium channels. Identified in potassium channel complexes containing KCND1, KCND2, KCND3, KCNIP1, KCNIP2, KCNIP3, KCNIP4, DPP6 and DPP10 (By similarity). The KCND2-KCNIP2 channel complex contains four KCND2 and four KCNIP2 subunits (PubMed:14623880, PubMed:14980201). Interacts with KCND2 (PubMed:10676964, PubMed:14623880, PubMed:14980201). Isoform 1 and isoform 3 interact with KCND3 isoform 1. Probably part of a complex consisting of KCNIP1, KCNIP2 isoform 3 and KCND2. At least isoform 2 and isoform 3 can self-associate to form homodimers and homotetramers. Isoform 3 interacts with KCNIP1 in a calcium-dependent manner.
Ion channel, Potassium channel, Voltage-gated channel
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For Research Use Only. Not For Clinical Use.