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KEAP1

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This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, IP, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, FuncS
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
WB, ICC/IF, FC, IHC-P
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