Loading...
KLHL21
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Squamous epithelial cells, Suprabasal keratinocytes)
Immune cell specificity
Group enriched (neutrophil, eosinophil)
Cell line specificity
Low cell line specificity
Interaction
Component of the BCR(KLHL21) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL21 and RBX1.
More Types Infomation
-
- Species Reactivity: Human
- Application: ELISA, IHC-P, WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.