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LAMA4

Binding to cells by a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Protein class

Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Leydig cells, Oligodendrocyte precursor cells, Fibroblasts, Microglial cells, Extravillous trophoblasts, Theca cells, Adipocytes, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, HSkMC, hTERT-RPE1, HUVEC TERT2, TIME)

Interaction

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-4 is a subunit of laminin-8 (laminin-411), laminin-9 (laminin-421) and laminin-14 (laminin-423).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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