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LIF

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes
Protein class

Cancer-related genes, Plasma proteins

Predicted location

Intracellular, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Glandular and luminal cells, Basal respiratory cells, Endometrial ciliated cells, granulocytes, Club cells, Fibroblasts)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (GAMG, hTEC/SVTERT24-B, hTERT-RPE1, U-138 MG, U-251 MG, U-87 MG)

Molecular function

Cytokine, Growth factor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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