Intracellular
Cell type enhanced (Syncytiotrophoblasts)
Not detected in immune cells
Low cell line specificity
Heterodimer with MBD2 (PubMed:10947852). Part of the NuRD and the MeCP1 complex (PubMed:12124384, PubMed:11756549, PubMed:15454082). Interacts with BCL6, HDAC1, MTA2, DNMT1, p66-alpha and p66-beta (PubMed:11102443, PubMed:12124384, PubMed:12183469, PubMed:11756549, PubMed:15454082). Does not interact with PWWP2A and PWWP2B (By similarity).
DNA-binding
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For Research Use Only. Not For Clinical Use.