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MEOX2

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Adipocytes, Leydig cells, Endothelial cells, Smooth muscle cells, Sertoli cells, Peritubular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (AN3-CA, U-138 MG)

Interaction

Interacts with RNF10 (PubMed:16335786). Interacts with TCF15 (By similarity).

Molecular function

Activator, Developmental protein, DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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