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MMP9

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Derivation:
Humanized
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Derivation:
Phage display library
Type:
Human antibody
Application:
ELISA
Derivation:
Phage display library
Type:
Human antibody
Application:
ELISA
Application:
ELISA
Application:
ELISA
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, Neut
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
ELISA, Neut
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, Neut
Species Reactivity:
Human
Type:
IgG1
Application:
Inhib, IHC-Fr, IP, IHC-P, WB, IHC, ICC
Species Reactivity:
Human
Type:
IgG
Application:
ELISA
Species Reactivity:
Human
Type:
IgG
Application:
ELISA
Species Reactivity:
Human
Type:
Fab
Application:
LMNX, ELISA
Derivation:
Phage display library
Type:
Human antibody
Application:
ELISA
Derivation:
Phage display library
Type:
Human antibody
Application:
ELISA
Species Reactivity:
Human
Application:
IHC-Fr, IHC-P
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
FC, IHC-P, WB
Species Reactivity:
Human, Rat, Cynomolgus
Type:
Mouse scFv
Application:
FC
Derivation:
ScFv library
Species Reactivity:
Human
Type:
Human scFv
Application:
Neut
Species Reactivity:
Human, Rat, Cynomolgus
Type:
Mouse Fab
Application:
FC
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