+ Filter
Loading...
MMRN1
Loading...Anti-MMRN1 Products
CompareCan't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Background
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Endothelial cells, Hepatic stellate cells)
Immune cell specificity
Group enriched (NK-cell, plasmacytoid DC)
Cell line specificity
Cell line enriched (HUVEC TERT2)
Interaction
Multimeric. Composed of varying sized, disulfide-linked multimers, the smallest of which is a homotrimer. Proteolysis of the promultimerin in the N-terminal region, leads to the mature p155 form that is stored in platelets. Interacts with factor V/Va.
More Types Infomation