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MT-CYB

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
Protein class

Disease related genes, Human disease related genes, Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Cardiomyocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (ASC diff, HeLa)

Interaction

The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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