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NEIL2
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Spermatogonia)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Binds EP300.
Molecular function
DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, FC, IP
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For Research Use Only. Not For Clinical Use.