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NEUROG2

This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Muller glia cells, Breast myoepithelial cells, Early spermatids, Spermatocytes, Late spermatids, Astrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (SH-SY5Y)

Interaction

Efficient DNA binding requires dimerization with another bHLH protein.

Molecular function

Activator, Developmental protein, DNA-binding

More Types Infomation

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