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NMT2

This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl group to the N-terminal glycine residue of many signaling proteins, including the human immunodeficiency virus type 1 (HIV-1) proteins, Gag and Nef. Alternative splicing results in multiple transcript variants.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatocytes, granulocytes)

Immune cell specificity

Group enriched (T-reg, naive CD4 T-cell, NK-cell, MAIT T-cell, memory CD4 T-cell, naive CD8 T-cell, basophil, eosinophil, memory CD8 T-cell, gdT-cell)

Cell line specificity

Cell line enhanced (fHDF/TERT166, TIME)

Molecular function

Acyltransferase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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