Loading...
NXN
Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Protein class
Disease related genes, Enzymes, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids, Microglial cells, Urothelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (HaCaT, HHSteC)
Interaction
Associates with the phosphatase 2A holoenzyme. Interacts with PPP2CA; the interaction is direct. Interacts with DVL1 (via PDZ domain); the interaction is direct and regulated by oxidative stress (By similarity).
Molecular function
Developmental protein, Oxidoreductase
More Types Infomation
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b, κ
- Application: WB, IP, IF, ELISA
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.