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OTX1
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Astrocytes, Respiratory ciliated cells, Basal respiratory cells, Ionocytes, Club cells, Suprabasal keratinocytes)
Immune cell specificity
Immune cell enriched (neutrophil)
Cell line specificity
Cell line enriched (THP-1)
Molecular function
Developmental protein, DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.