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P2RY1

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Protein class

G-protein coupled receptors, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Squamous epithelial cells, Distal enterocytes, Bipolar cells, Cholangiocytes, Kupffer cells)

Immune cell specificity

Group enriched (basophil, non-classical monocyte)

Cell line specificity

Cell line enriched (HEL)

Molecular function

G-protein coupled receptor, Receptor, Transducer

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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