Intracellular
Cell type enhanced (Distal enterocytes, Microglial cells, Melanocytes, Sertoli cells, granulocytes)
Low immune cell specificity
Cell line enhanced (Daudi, HMC-1, SK-MEL-30)
Interacts with FYN. When phosphorylated, interacts with CSK. Interacts with SLC9A3R1/EBP50. In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation. Interacts with LYN on plasma membrane lipid rafts. Identified in a complex with LYN and STAT3.
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For Research Use Only. Not For Clinical Use.