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PDLIM1

This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Proximal enterocytes, Basal prostatic cells, Paneth cells, Basal respiratory cells)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell, eosinophil)

Cell line specificity

Cell line enhanced (HaCaT, Hep G2, HHSteC)

Interaction

Interacts with ACTN1, ACTN2 and ACTN4 (PubMed:10861853, PubMed:10753915, PubMed:11110697). Interacts with PDLIM4 (By similarity).

More Types Infomation

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