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PI15
This gene encodes a trypsin inhibitor. The protein shares similarity to insect venom allergens, mammalian testis-specific proteins and plant pathogenesis-related proteins. It is frequently expressed in human neuroblastoma and glioblastoma cell lines, and thus may play a role in the central nervous system.
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Breast glandular cells, Basal prostatic cells, Smooth muscle cells, Prostatic glandular cells, Urothelial cells, Breast myoepithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (AF22, SH-SY5Y, SK-MEL-30, U-266/70)
Molecular function
Developmental protein, Protease inhibitor
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.