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PIEZO1
The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015]
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Pancreatic endocrine cells, Alveolar cells type 1)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (MCF7)
Interaction
Homotrimer. Interacts with PKD2. Interacts with STOML3.
Molecular function
Ion channel
More Types Infomation
- Recombinant Mouse Anti-PIEZO1 Monoclonal Antibody (2-10) (MRO-1281-CN)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG2a
- Application: WB, IHC, IF
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For Research Use Only. Not For Clinical Use.