Enzymes, Metabolic proteins
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with PCNA (PubMed:14992725). Interacts with PAXX; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL (PubMed:30250067). Interacts with XRCC4; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL (PubMed:30250067). Interacts with NHEJ1/XLF; promoting POLL recruitment to double-strand breaks (DSBs) and stimulation of the end-filling activity of POLL (PubMed:30250067).
DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase
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For Research Use Only. Not For Clinical Use.