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polysialic acid
Loading...Anti-polysialic acid ProductsBackground
Anti-polysialic acid Products
- Mouse Anti-Polysialic Acid Antibody (clone mAb735), mRNA (PABL-309-mRNA)
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- Recombinant Human Anti-polysialic acid Antibody Fab Fragment (MHH-787-F(E))
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- Derivation: Human
- Type: Fab
- Application: WB, IF, FuncS
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- Recombinant Anti-polysialic acid Antibody Fab Fragment (MOB-787-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: ELISA, RIA, FuncS
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- Recombinant Anti-polysialic acid Antibody scFv Fragment (MOB-787-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, WB, IF, FuncS
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For Research Use Only. Not For Clinical Use.
Background
Polysialic acid is an unusual posttranslational modification that occurs on neural cell adhesion molecules (NCAM). Polysialic acid is considerably anionic. This strong negative charge gives this modification the ability to change the protein's surface charge and binding ability. In the synapse, polysialation of NCAM prevents its ability to bind to NCAM's on the adjacent membrane.