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PPP1R14A
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Sertoli cells, Peritubular cells, Smooth muscle cells, Granulosa cells, Leydig cells, Adipocytes)
Immune cell specificity
Group enriched (memory B-cell, naive B-cell, plasmacytoid DC)
Cell line specificity
Group enriched (A549, EFO-21, K-562)
Molecular function
Protein phosphatase inhibitor
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB
- Recombinant Mouse Anti-Human PPP1R14A Antibody (MOB-0721MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.