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PPP1R1B

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class

Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Undifferentiated cells, Intestinal goblet cells, Urothelial cells, Distal enterocytes, Melanocytes, Paneth cells, Distal tubular cells)

Immune cell specificity

Immune cell enriched (eosinophil)

Cell line specificity

Cell line enhanced (ASC diff, CAPAN-2, HSkMC, OE19, SCLC-21H)

Molecular function

Protein phosphatase inhibitor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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